Numbing cream off of Amazon works for a brief sigh of relief. I use it on my dogs too.

I’ve been on both Enbrel and Humira - at the moment still on Humira which works for me. Both auto inject pens which didn’t bother me at all - a bit of a sting for a few seconds and that was it. Really nothing to worry about! And lucky me, never felt nauseous, maybe slight fatigue the next day.

I've done both. Humira did not work, but Enbrel did. I just went back on Enbrel after 3 years of trying other meds. I am doing good after only one month! I am so thankful. The auto injectors work about the same. This time I am on Enbrel minis. I have a reusable injector (which is cool) and there's less waste. Hope it works for you!

Haven't used Enbrel, but I take Methotrexate and it is very effective.so far.

I am now on Enbrel and have been for quite a while, it has decreased my pain, BUT when the rain comes, I am in so much pain, I have good days and bad days, I just take one day at a time and pray they come up with a cure, but then how will the pharmaceutical companies make their money?