Simponi Aria (Golimumab) for Rheumatoid Arthritis
Overview
- Simponi Aria is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe rheumatoid arthritis.
- It is used in combination with methotrexate.
- Simponi Aria is also known by its drug name, golimumab.
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Simponi Aria (Golimumab) for Rheumatoid Arthritis
Overview:
- Simponi Aria is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe rheumatoid arthritis.
- It is used in combination with methotrexate.
- Simponi Aria is also known by its drug name, golimumab.
- It is a biologic disease-modifying antirheumatic drug (DMARD).
Mechanism of Action:
- Simponi Aria is a genetically engineered antibody.
- It works by binding to tumor necrosis factor alpha (TNF-α), a chemical messenger involved in autoimmune attacks.
- This binding prevents TNF-α from signaling the immune system to attack the body’s connective tissues.
Administration:
- Administered as an intravenous infusion (slow injection into your vein) by a healthcare professional.
- Given every 8 weeks after initial loading doses.
Common Side Effects:
- Respiratory tract infections
- Viral infections
- Elevated liver enzymes
- Low white blood cell counts
- Bronchitis
- High blood pressure
- Rash
Rare but Serious Side Effects:
- Severe infections
- Hepatitis B virus reactivation
- Increased risk for lymphoma and other cancers
- Heart failure
- Nerve damage
- Lupus-like syndrome
- Severe allergic reactions
Financial Assistance:
- For eligible patients, the Janssen CarePath Savings Program may allow you to pay $5 for each Simponi injection.
- Eligibility: Must use private or commercial health insurance to cover a portion of medication costs for Simponi Aria. No income requirement.
For more details, you can visit:
- [Simponi Aria — Janssen](https://www.simponiaria.com/)
- [Golimumab for Infusion (Simponi Aria) — Johns Hopkins Arthritis Center](https://www.hopkinsarthritis.org/patient-corner...)
July 19, 2024
What will you use next? I'm also going to wait for the 4th treatment before beginning a new medication.
May 21, 2023
Same. My 4th one is coming up in June and if no more improvement will try something else. It actually spread into my ankles and feet since beginning treatments. They bother me at night so at least I get through the day
April 25, 2023
Thank you, it's so weird because my 1st treatment made such a difference. Than I felt it wear off which I was told would be normal the closer I get to my treatments. But when I did receive treatment I felt worse than the first time🙄. So I've been just dealing with pain and fatigue🤷♀️. Third treatment should be soon so lets see.🩷
April 11, 2023
I had my first treatment back in Feb. And it worked but my second treatment is not as effectulive as the first. I'llbask about Acterma.
April 3, 2023