when I was just on Plaquenil itself there were days of flare activity becoming difficult to manage without having compression socks and/or compression gloves at the time. Less pain did happen two to three weeks after the Methotrexate injection began. I noticed this positive change as the compression gloves were no longer needed to be used as frequently as they were prior to just starting the medication.

Every person is different when taking medication. In this case, I chose to take Methotrexate injection rather than the pill form for personal reasons. I highly suggest to speak with your specialist or even ask questions to local pharmacist as they should be able to provide further detail with side effect activity.

For me I think my flares get worse or more frequent with the weather changes and as I've gotten older and lived with ra longer..I hope if you have one it goes easy on you😊

Strangely the steroid pills do nothing for me except for helping a case of poison ivy rash. I get a big dose of steroids by iv and immediately bounce back. Doesn't last but a few weeks sometimes. For me.

Not sure if the RA is getting meaner or my age is making me less tolerable. The fatigue sure sucks the getupandgo right out.

Esther, my RA was doing pretty good since they upped my dose. The holidays put me in a little tailspin. Knock on wood I haven't had a bad flare since the new dose. They gave me medrol for 3 months it was so bad. Stress is really bad for this disease. I hope the medrol helps. 🙏❤️