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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Has Anyone Experienced Kidney Pain After Methotrexate

A myRAteam Member asked a question 💭
Ireland, IN

I started methotrexate injections 20 mg per week. After the second injection on the following day I started to experience pain in my left side under the ribs. I consulted my gp . He said it wasn’t connected to methotrexate. He put me on antibiotics as there was traces of blood in urine. After two courses of antibiotics the pain is still there. I also had an ultrasound scan which showed inflammation in the left kidney. Any advice on what to do next.

April 27, 2023
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A myRAteam Member

I would stop the Methotrexate and see if it stops.

April 27, 2023
A myRAteam Member

Please let your Rheumatologist know what is going on....you may need a referral to a Nephrologist.

April 27, 2023
A myRAteam Member

How are you doing? Kidney damage is listed as a rare side effect of methotrexate.

May 1, 2023
A myRAteam Member

I seem to be having the same issue, but in the early stages. My RA saw a slight drop in kidney function, and there is consistent blood in my urine. my nephrologist took me off the methotrexate on Oct 1 - I go back on Nov 9. Hoping that I won't have to go for a biopsy

October 25, 2023
A myRAteam Member

I had methotrexate for a long time, it was stopped as it damaged my liver. I now have cirrhosis of the liver, also have been diagnosed with sjorgens and pancreitis and am unable to eat some foods because of reactions. I have biologicals every 6 months. All this has built up over 30 years 😭

April 30, 2023

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