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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Has Anyone Had Side Effects From Sulfasalazine And If So What Did You Experience?

A myRAteam Member asked a question 💭
Ballymena, UK
October 21, 2024
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A myRAteam Member

Thank you Veronica for your kind words. I hope your blood work settles soon. ❤️

October 21, 2024
A myRAteam Member

yes, when we tried the medication I had issues with eyes getting blurry. I thought it was my glasses at first but it was actually the medication itself.

October 21, 2024
A myRAteam Member

Hi Hilary, I haven’t taken this medication. I’ve been on mtx for almost 4 years. Lately my blood work numbers have been off. So far my dr has been adjusting the mtx dosage. If blood work issues continue this is the medication she said I should consider. I’m very interested to hear others responses. Hope today is being kind to you 🤗

October 21, 2024
A myRAteam Member

Sulfasalazine can cause side effects. Here are some common and serious side effects:

Common Side Effects:
- Yellow or orange discoloration of urine or skin
- Diarrhea
- Headache
- Loss of appetite
- Upset stomach
- Vomiting
- Stomach pain

Serious Side Effects
- Rash, hives, itching, or peeling or blistering skin
- Show Full Answer

Sulfasalazine can cause side effects. Here are some common and serious side effects:

Common Side Effects:
- Yellow or orange discoloration of urine or skin
- Diarrhea
- Headache
- Loss of appetite
- Upset stomach
- Vomiting
- Stomach pain

Serious Side Effects:
- Rash, hives, itching, or peeling or blistering skin
- Swelling of the eyes, face, lips, tongue, mouth, or throat
- Difficulty breathing or swallowing
- Swollen glands
- Fever, sore throat, chills, cough, night sweats, and other signs of infection
- Pale skin, tiredness, or shortness of breath
- Joint or muscle aches
- Yellowing of the skin or eyes
- Pain in the right upper part of the stomach
- Difficult or painful urination or cloudy, discolored, or bloody urine
- Chest pain
- New or worsening cough
- Unusual bleeding or bruising
- Weakness
- Seizures

If you experience any serious side effects, stop taking sulfasalazine and contact your doctor immediately.

October 21, 2024
A myRAteam Member

That’s interesting because that also happened to me along with a host of other things. I was on Sulfasalazine right at the beginning when I was diagnosed with RA but now I’m not tolerating it at all.

October 21, 2024

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