It seems like you're asking about problems related to methotrexate treatment. Here are some key points based on the provided context:

Common Side Effects
- Gastrointestinal Issues: Nausea, stomach upset, loose stool, and mouth ulcers.
- Hair Loss: Some patients may experience hair thinning or loss.
- Liver Problems: Meth Show Full Answer

It seems like you're asking about problems related to methotrexate treatment. Here are some key points based on the provided context:

Common Side Effects:
- Gastrointestinal Issues: Nausea, stomach upset, loose stool, and mouth ulcers.
- Hair Loss: Some patients may experience hair thinning or loss.
- Liver Problems: Methotrexate can cause liver damage, especially in patients with psoriatic arthritis or psoriasis.
- Other Issues: Abdominal pain, indigestion, rash, common cold symptoms, diarrhea, vomiting, headache, bronchitis, low blood cell counts, dizziness, sensitivity to sunlight, and skin sores.

Serious Side Effects:
- Liver Damage: Symptoms include extreme tiredness, lack of energy, loss of appetite, pain in the upper right part of the stomach, yellowing of the skin or eyes, and flu-like symptoms.
- Lung Damage: Symptoms include dry cough and difficulty breathing.
- Allergic Reactions: Severe reactions can include difficulty breathing or swelling in the face, throat, eyes, lips, or tongue.
- Reproductive Issues: Low sperm cell count and menstrual dysfunction.
- Fetal Harm: Methotrexate can cause fetal harm or death, so it is recommended to stop using the drug at least three months prior to attempting pregnancy.

Monitoring and Precautions:
- Liver Biopsies: Your doctor may order liver biopsies before and during treatment to monitor liver health.
- Alcohol Use: Consult your doctor about the safe use of alcoholic beverages while taking methotrexate.

Administration:
- Forms: Methotrexate can be administered as a weekly pill or a subcutaneous injection.
- Self-Administration: If deemed appropriate by your doctor, you may self-inject at home using a prefilled, single-use syringe.

Recommendations:
- Contraceptives: The American College of Rheumatology recommends the use of hormonal contraceptives and intrauterine devices (IUDs) for patients on methotrexate.

For more detailed information, you can refer to the sources provided in the context.

 This AI-generated response comes from myRAteam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

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