The red, swollen, itchy mark around the injection site after using the Humira injection pen can be a common reaction. This might occur due to several reasons:

- **Skin Reaction**: The skin might react to the physical act of injection or to components in the injection solution
- **Injection Technique**: Improper injection Show Full Answer

The red, swollen, itchy mark around the injection site after using the Humira injection pen can be a common reaction. This might occur due to several reasons:

- **Skin Reaction**: The skin might react to the physical act of injection or to components in the injection solution.
- **Injection Technique**: Improper injection technique or injecting into an area where the skin is tender, bruised, red, or hard can cause irritation.
- **Sensitivity to Ingredients**: Some individuals might have a sensitivity to ingredients in the Humira formulation, though the citrate-free version of Humira has been noted to reduce the burning sensation associated with injections.

It's important to rotate injection sites and avoid injecting into areas where the skin is compromised. If the reaction is severe or persistent, consulting a healthcare provider is advisable to ensure it's not indicative of a more serious issue.

 This AI-generated response comes from myRAteam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

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