I take 10 mg Leflunomide daily, no side effects. Started with Methrotrexate and then Hydroxychloroquine had awful side effects on both of those drugs, could not tolerate had to go off. Been a year on Leflunomide, still have some sleep issues, some aching, stiffness, soreness and fatigue on and off but no big nasty flares. I don’t think any of these drugs are 100%, unless one is blessed with going into remission.

I take 10 mg Leflunomide daily, with Panquil and very few side effects. a bit of itching, mostly on my back. These 2 are working really well for me. I take other OTC vitamins for hair, skin and nails + Omega 3 fish oil, collagen every day.

I take luflunomide 20mg per day, for 4 years no problem yet.

I have been on leflunomide 20mg for 5 weeks. The only side effect that I know is that I used to be constipated, but not anymore. I don't have diarrhea though - Just not constipated. I still have pain and swelling in hands and feet but it is too soon to tell. I see the Rheumatologist in another 3 weeks. At that point, we will be taking labs.

Huntley, thank you.