Most RA drugs take quite a while to work. Unlikely it's the Plaquenil causing new pain, more likely it's the disease not yet under control. But check with your doc if you're worried. FYI_ Plaquenil has helped me for many years.

No don't be discouraged takes awhile

Speak to your Dr and if ok I always state this and follow this . I allow every med a few months to work . I have done 4 to 6 months time frames. If there is a severe reaction that's different and then follow up with your doctor

For me it was reversed, was catatonic on methotrexate, feel much better on plaquinil ,

Give it time