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Methotrexate Oral Vs Injection

A myRAteam Member asked a question 💭
Wind Gap, PA

I’m anticipating that my rheum will prescribe methotrexate in the next month or so. I’ve heard lots of people have bad side effects to the pills and I already have IBS. My question is - has anyone ever started on injections without first trying pills? Or is it normal to have to try the pills first? I’m a nurse, not afraid of needles or giving myself an injection. Thanks!

August 7, 2020
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A myRAteam Member

I was advised NOT to take all the pills at once but to take a few with a meal intermittently within 24 hours. So let's say 2 for breakfast, 2 for lunch, 2 for dinner (or whatever your dosage is) You can confirm with your pharmacist about this but when I took all the pills at once, I had GI issues and headache - this method works perfect and I barely even notice I'm taking any medication Good luck !

August 14, 2020
A myRAteam Member

I started on injections first. That's the only thing I've been on since I started then she add the pill plaquenil with it. But I have been doing the shot since January I have no problem giving myself the shot it is the side effects from the medicine it's self.

August 13, 2020
A myRAteam Member

I started on the injection first. So I only know of the injection. Terrible side effects. So I was put on folic acid to help with that. Have a good day.

August 8, 2020
A myRAteam Member

I just met with my Dr today. I have to be on methotrexate and folic acid.

August 7, 2020
A myRAteam Member

I started with injection

August 10, 2020

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