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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Prednisone Side Effects?

A myRAteam Member asked a question 💭
Cleveland, OH

Anyone suffer from side effects of long term use of prednisone? I cannot sleep more than 2hrs at a time. Normally I sleep 4-6 on average off the drug. I also have the worst heartburn ever!! Ugh.

February 7, 2019
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A myRAteam Member

I have been on 10mg a day of prednisone since 2011, and tapering doses of 50 mg tapered down down to 10 for flare ups. I have experienced Bi Polar episodes of mania followed by depression 3 times. Reaked havoc on my life!! My Rheumy never told me that Mood Disorders are the main and most common side effect of Prednisone since it's also a hormone in addition to the antinflammatory.

It causes Bi Polar behaviors and I am getting weaned off of it permanently. It has totally destroyed my life.

February 20, 2019
A myRAteam Member

I was on humerus. Tried going off prednisone. Started having severe shortness of breath. Legs and feet swelled up. My Rheumatologist took me off humerus. Everything went back to normal within a couple of days.

February 12, 2019
A myRAteam Member

Am off prednisone after 2 yrs. On humera but have bad shortness of breath since quitting prednisone 2 weeks ago, going for cat scan of chest, anyone have anything like this!

February 11, 2019
A myRAteam Member

I have been on prednisone for 7yrs. Keep trying to get off of it but the withdrawal is horrible!
Like you, I don't sleep much 1-2 hrs at a time. Dozy all day and clumsy and very forgetful!
Pretty sure lack of sleep will do this to a person.

Time for a real heart to heart with my Rheumatologist and GP.

February 10, 2019
A myRAteam Member

Prednisone is not good for you,it may help with inflamation but has bad side effects if taking for a long period of time.

February 9, 2019

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