If your lips were real swollen I can see why they would hesitate trying another biologic. I had a seizure when I was on Humira, and now I can't be on any TNF blockers (and those were the only biologics that worked). I am on Orencia now, but it doesn't seem to do much. Hope you find something that works for you! Hugs!

I was severely allergic to ALL OF the drugs & biologics. I'm currently on Xeljanz and aside from headaches, I am doing well!

I was allergic to Remmicde Humiria & Enbrel . Now I am on Orencia and loving it.. There are so many good meds out there.

Some of the biologics have similar chemical make up, and similar ways that they work in your body. If you are allergic to Humira (as I was also), many of the other biologics function the same way. I do know that Xeljanz functions in a different manner, and its chemical make up is different. Perhaps you might suggest that to your rheumatologist when you go the next time. I'm so sorry. It can be so discouraging when you think you are going to be on a drug that's going to help and then WAM, you can't take it. KEEP YOUR SPIRITS UP!! There are new drugs coming down the pike much faster now than ever before. I hope you are feeling better soon.

It’s a pill you take once a day